ProLon Fasting Mimicking Diet

ProLon Fasting Mimicking Diet

RegenLife Centers offers the ProLon 5-Day Fasting Mimicking Diet in Cincinnati, OH, Montgomery, OH, and Edgewood, KY for patients seeking a doctor-supported metabolic reset. Backed by over 20 years of scientific research, ProLon is a plant-based program that lets you eat specially formulated meals and snacks while your body enters a fasting-like state — supporting healthy weight management, visceral fat reduction, and cellular renewal through autophagy. Our Greater Cincinnati providers help determine if ProLon is the right fit for your wellness goals and guide you through each cycle.

What is the ProLon Fasting Mimicking Diet?

ProLon is a clinically developed, plant-based 5-Day Fasting Mimicking Diet (FMD) — a precisely formulated nutrition program that provides food in quantities and combinations that do not trigger the body's nutrient-sensing pathways associated with normal eating. This allows your body to experience the metabolic and cellular benefits of a prolonged fast while still receiving nourishment.

Unlike juice cleanses or crash diets, ProLon was developed through peer-reviewed research at the University of Southern California and is designed to be repeated on a monthly basis as part of a broader lifestyle strategy. The program is intended to complement — not replace — your regular diet and any medically guided wellness plan.

At RegenLife, our providers integrate ProLon into a comprehensive approach to metabolic health, helping you understand how the program fits with your individual health profile, goals, and any existing conditions.

What's Inside the ProLon Kit

Each ProLon kit is a complete 5-day program — everything you need is included and labeled by day:

Plant-Based Meals & Snacks

Five full days of pre-portioned, carefully formulated plant-based soups, crackers, bars, and olives designed to keep the body in a fasting-like state.

Includes:

  • Day-labeled meal packs
  • Soups, nut bars & olives
  • Balanced macro ratios
  • No animal products

Herbal Teas & Beverages

A selection of herbal teas and L-Drink (a proprietary glycerol-based beverage) to support hydration and energy during the program days.

Includes:

  • Herbal teas included
  • L-Drink energy support
  • Hydration guidance
  • Coffee allowed in moderation

Supplements

Daily supplement packs with vitamins, minerals, and omega-3 fatty acids to support nutritional completeness throughout the fasting-mimicking period.

Includes:

  • Daily vitamin packs
  • Omega-3 fatty acids
  • Mineral support
  • Pre-portioned per day

Guidance & Education Materials

Step-by-step daily instructions, nutrition education resources, and healthy-lifestyle support tools — including recipes for transitioning back to regular eating.

Includes:

  • Day-by-day instructions
  • Nutrition education
  • Healthy recipe guides
  • Re-feeding transition tips

Potential Benefits of the ProLon Program

ProLon is designed to support a range of wellness outcomes, particularly when completed as consecutive monthly cycles under provider guidance:

Weight & Body Composition

  • • Healthy weight management
  • • Reduction of visceral fat
  • • Preservation of lean muscle
  • • Reduced food cravings
  • • Improved portion control

Metabolic Health

  • • Metabolic balance support
  • • Blood sugar regulation
  • • Improved lipid markers
  • • Reduced inflammation
  • • Insulin sensitivity support

Cellular & Longevity

  • • Autophagy activation
  • • Cellular renewal support
  • • Fresh start for habits
  • • Longevity goal support
  • • Increased energy awareness

Some benefits are associated with consecutive monthly ProLon cycles. Individual results vary. Consult your RegenLife provider to understand what outcomes are realistic for your specific health profile.

What is Autophagy?

During prolonged fasting, the body activates autophagy — a natural cellular “clean-up” system that breaks down and recycles old, damaged, or dysfunctional cellular components. The word itself comes from the Greek for “self-eating,” and the process was awarded the Nobel Prize in Physiology or Medicine in 2016.

What autophagy does

Autophagy recycles damaged organelles, misfolded proteins, and other cellular debris — supporting cellular renewal and efficient function.

Why ProLon activates it

ProLon's precisely calibrated macronutrient profile keeps nutrient-sensing pathways in a low-activation state, similar to a water-only fast, allowing autophagy to proceed.

Why it matters

Cellular renewal through autophagy is linked to healthy aging, metabolic resilience, and reduced chronic disease risk.

Why not fast alone?

Extended water fasting without guidance is difficult to sustain, nutritionally risky, and not appropriate for everyone. ProLon provides the benefits of prolonged fasting with structured nutritional support.

ProLon vs. Intermittent Fasting

Intermittent fasting (IF) limits calories or eating windows on a daily basis — typically 16 to 24 hours at a time. While IF has well-documented benefits, it operates on a different timescale and mechanism than ProLon:

1

Duration

Intermittent fasting works in daily cycles (16–24 hours). ProLon sustains a fasting-like state across 5 consecutive days, reaching metabolic milestones that shorter windows cannot.

2

Cellular Activation

Multi-day fasting is needed to robustly activate autophagy and trigger deeper metabolic shifts. ProLon's formulation is engineered to reach these thresholds.

3

Nutritional Safety

Unlike extended water fasting, ProLon provides vitamins, minerals, and phytonutrients calibrated to support the body throughout the 5-day period without triggering nutrient-sensing pathways.

4

Habit Reset

Many patients use ProLon as a structured reset — breaking cravings and re-calibrating appetite signals in a way that short-window IF does not typically achieve.

Who is ProLon For?

ProLon is well suited for adults who want to take a structured, science-backed approach to one or more of the following goals:

  • Jumpstart healthier eating habits after a period of poor nutrition
  • Support healthy weight management and reduce visceral fat
  • Improve metabolic markers and insulin sensitivity
  • Support longevity and cellular health goals
  • Complement a medically guided lifestyle or weight-management program
  • Break chronic food cravings and recalibrate portion awareness

ProLon is not appropriate for everyone. It is not recommended for pregnant or breastfeeding women, individuals under 18 years of age, or those with certain medical conditions. Your RegenLife provider will review your health history and determine whether ProLon is a safe and appropriate fit before you begin.

How to Get Started with ProLon at RegenLife

Getting started with ProLon at RegenLife is straightforward. Ask your RegenLife provider whether the ProLon program is right for you at your next visit, or call any of our locations — Cincinnati OH, Montgomery OH, or Edgewood KY — to schedule a consultation.

Patients who are already enrolled in the ProLon program can also access the program portal directly at prolonlife.com/regenlifecenters.

Get In Touch

Schedule Your ProLon Fasting Mimicking Diet

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Cincinnati

3328 Westbourne Dr,

Cincinnati, OH 45248

(513) 922-2204

Edgewood

162 Barnwood Dr,

Edgewood, KY 41017

(859) 331-4159

Montgomery

9989 Montgomery Road,

Montgomery, OH 45242

(513) 922-2204

We accept most major insurance plans

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Our Locations

Cincinnati Clinic

3328 Westbourne Dr,

Cincinnati, OH 45248

(513) 922-2204

Edgewood Clinic

162 Barnwood Dr,

Edgewood, KY 41017

(859) 331-4159

Montgomery Clinic

9989 Montgomery Road,

Montgomery, OH 45242

(513) 922-2204

Hours of Operation

Monday – Friday8:00am – 5:00pm
Saturday9:00am – 3:30pm
SundayClosed
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